Copenhagen Aging and Midlife Biobank – University of Copenhagen

Copenhagen Aging and Midlife Biobank

The Copenhagen Aging and Midlife Biobank (CAMB) has been established to contribute new knowledge on the life course determinants of health and early aging in mid- and late life, and is designed with particular emphasis on the earlier stages of the aging process. 

CAMB includes participants from three earlier established cohort studies with data on the first half of life: The Metropolit 1953 Danish Male Birth Cohort (MP), The Copenhagen Perinatal Cohort (CPC) (born 1959-61), and The Danish Longitudinal Study on Work, Unemployment and Health (DALWUH) (born 1949 or 1959). 

In total, 17,937 cohort members (aged 49-61 years) were invited to participate in the study (MP: 7,750, CPC: 5,282, and DALWUH: 4,906); 7,191 (40%) (4,954 men and 2,234 women) completed a postal questionnaire covering psychosocial, behavioral, health-related and social variables and 5,576 (31%) (3,819 men and 1,754 women) in addition participated in a clinical examination as well as physical and cognitive tests. Non-fasting blood samples were collected and analyzed for low grade inflammation, standard lipid and glucose profiles. From each participant, several samples of plasma, serum, and DNA were stored in a research bio-bank for future use.

Linking CAMB to national registers provide outstanding possibilities to study the importance of pre- and perinatal factors, factors in childhood and early adulthood for early signs of aging in late midlife.